Endocrine Abstracts

Ipilimumab is a monoclonal antibody that had been shown significantly to improve survival in cases of metastatic melanoma. It blocks cytotoxic T-lymphocyte antigen 4(CTLA4) resulting in T-cell activation, proliferation and antitumor response. However recently an emerging clinical entities of different endocrinopathies have been reported in patients on ipilimumab. These are mainly related to lymphocytic hypophysistis causing anterior hypop...

Ipilimumab is a monoclonal antibody that had been shown significantly to improve survival in cases of metastatic melanoma. It blocks cytotoxic T-lymphocyte antigen 4(CTLA4) resulting in T-cell activation, proliferation and antitumor response. However recently an emerging clinical entities of different endocrinopathies have been reported in patients on ipilimumab. These are mainly related to lymphocytic hypophysistis causing anterior hypop...

Aim: To assess the appropriateness of parathyroid imaging performed in patients with primary hyperparathyroidism at the United Lincolnshire Hospital NHS Trust from 2018 to 2019.Background: Primary hyperparathyroidism (PHPT) is a clinical and biochemical diagnosis. Reported sensitivity for imaging localisation of parathyroid adenomas for ultrasound and sestamibi scans are not high at 65 to 85% and 71 to 92%, respectively. Surgeons use combined ultrasound ...